The following table presents various preventative treatments which have been scientifically proven to be effective against migraine.

Please note that medicines have two names, the pharmacological and the commercial names of the substance. The names of generic drugs often start with apo-. If you want to provide information to your doctor, download the following article: PDF article Pringsheim. If you want to know what “scientifically proven” means, click here. Substance Commercial name Beta-blockers
(Slow down heart rate diminish blood pressure) Propanolol Inderal Atenolol Tenormin Nadolol Corgard Other anti-hypertensive drugs
(diminish blood pressure) Candesartan Atacand Flunarizine Sibelium Lisinopril Prinivil Antidepressants
(treat migraine even without depression) Amitriptyline Elavil Venlafaxine Effexor Nortriptyline Aventyl Anti-convulsive drugs
(drugs created to treat epilepsy) Topiramate Topamax Valproic acid Epival Gabapentin Neurontin Natural products
(scientifically tested) Vitamin B2
Coenzyme Q10 Petasites Hybridus 
Same name, natural products
Petadolex (Natural product store) Other Please note that methysergide (Sansert) and pizotifen (Sandomigran) are no longer available. Petasites hybdridus (butterbur) has been associated with toxicity to the liver in rare cases. More data should be available in 2015. If you suffer from liver disease you should not take this product. Please discuss the risks of petasites with your doctor before starting it.